Abstract | OBJECTIVES: METHODS: RESULTS: In 32 patients showing a high MIB-1 index (percentage of cells labeled with MIB-1 >/=26.4%), the cumulative 5- and 8-year survival rates were 75.8 and 61.5%, respectively, significantly better (P < 0.05) than those in 35 patients with a low MIB-1 index (<26.4%) (59.6 and 41.1%, respectively). Serum squamous cell carcinoma antigen levels, an index of the response to radiation therapy, decreased to </=2.0 ng/mL in 100 and 68% of patients in the high and low MIB-1 index groups, respectively (P < 0.05). CONCLUSION:
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Authors | M Suzuki, S Tsukagoshi, Y Saga, M Ohwada, I Sato |
Journal | Gynecologic oncology
(Gynecol Oncol)
Vol. 79
Issue 2
Pg. 300-4
(Nov 2000)
ISSN: 0090-8258 [Print] United States |
PMID | 11063661
(Publication Type: Comparative Study, Journal Article)
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Copyright | Copyright 2000 Academic Press. |
Chemical References |
- Antibodies, Monoclonal
- Antigens, Neoplasm
- Antigens, Nuclear
- Biomarkers, Tumor
- Ki-67 Antigen
- Nuclear Proteins
- Serpins
- squamous cell carcinoma-related antigen
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Antibodies, Monoclonal
(biosynthesis, immunology)
- Antigens, Neoplasm
(blood)
- Antigens, Nuclear
- Antineoplastic Combined Chemotherapy Protocols
(therapeutic use)
- Biomarkers, Tumor
(biosynthesis, blood, immunology)
- Cell Division
(immunology)
- Chemotherapy, Adjuvant
- Female
- Humans
- Ki-67 Antigen
(immunology)
- Middle Aged
- Nuclear Proteins
(biosynthesis, immunology)
- Prognosis
- Retrospective Studies
- Serpins
- Survival Analysis
- Uterine Cervical Neoplasms
(immunology, pathology, radiotherapy)
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