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Pain is significantly reduced by cryoablation therapy in patients with lateral minithoracotomy.

AbstractBACKGROUND:
In minimally invasive cardiac surgery use of a lateral minithoracotomy is associated with early postoperative rehabilitation but also relatively high pain levels during the first 3 postoperative days. Cryoablation therapy was evaluated prospectively.
METHODS:
From April 1999 until September 1999, 57 patients underwent lateral minithoracotomy for mitral valve operation (n = 18) or minimally invasive direct coronary artery bypass grafting (n = 39). Intraoperatively, patients were randomly assigned to cryoablation or intercostal application of local anesthetic agents. A standardized questionnaire was used for prospective pain assessment on postoperative days 1 to 7.
RESULTS:
From postoperative day 1 to 7 pain levels declined in all groups. Overall pain levels were significantly lower in the cryo group than in the control group (p < 0.0001, GLM). According to diagnoses, pain levels were significantly lower after MIDCABG and cryo versus control; after mitral valve operation they were lower in the cryo group and almost reached significance.
CONCLUSIONS:
Cryoablation is easy to perform and leads to a significant reduction in pain and lower request for additional pain medication after lateral minithoracotomy in minimally invasive cardiac operation.
AuthorsJ Bucerius, S Metz, T Walther, N Doll, V Falk, A Diegeler, R Autschbach, F W Mohr
JournalThe Annals of thoracic surgery (Ann Thorac Surg) Vol. 70 Issue 3 Pg. 1100-4 (Sep 2000) ISSN: 0003-4975 [Print] Netherlands
PMID11016387 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
Chemical References
  • Anesthetics, Local
Topics
  • Anesthetics, Local (therapeutic use)
  • Coronary Artery Bypass (methods)
  • Cryosurgery
  • Female
  • Heart Valve Prosthesis Implantation (methods)
  • Humans
  • Male
  • Middle Aged
  • Minimally Invasive Surgical Procedures
  • Mitral Valve (surgery)
  • Pain, Postoperative (surgery)
  • Thoracotomy (methods)

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