Abstract | PURPOSE: To study the efficacy of intravitreally injected plain and liposome encapsulated fluconazole in the doses of 100 and 200 microg in Candidal endophthalmitis in rabbit eyes. METHOD:
Endophthalmitis was induced by injecting Candida albicans (1000 CFU/0.1 ml). Seventy two hours after inoculation, plain and liposome encapsulated fluconazole (REVs) were injected. At day 16 sterility was studied using vitreous culture. RESULTS: CONCLUSION:
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Authors | S K Gupta, N Dhingra, T Velpandian, J Jaiswal |
Journal | Acta ophthalmologica Scandinavica
(Acta Ophthalmol Scand)
Vol. 78
Issue 4
Pg. 448-50
(Aug 2000)
ISSN: 1395-3907 [Print] Denmark |
PMID | 10990049
(Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Antifungal Agents
- Liposomes
- Fluconazole
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Topics |
- Animals
- Antifungal Agents
(administration & dosage)
- Candida albicans
- Candidiasis
(drug therapy, microbiology)
- Drug Delivery Systems
- Endophthalmitis
(drug therapy, microbiology)
- Eye Infections, Fungal
(drug therapy, microbiology)
- Female
- Fluconazole
(administration & dosage)
- Injections
- Liposomes
- Male
- Rabbits
- Safety
- Vitreous Body
(drug effects)
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