[Serotonin syndrome secondary to the use of sertraline and metoclopramide].

Abstract

The authors report the case of a patient who developed a serotonin syndrome after taking sertraline and metoclopramide. The symptoms included malaise, cardiac arrhythmia, sudation, hyperreflexia, sialosis, diarrhea and were improved by cyproheptadine. The authors review the physiological bases of the serotonin syndrome, its incidence, clinical manifestations and treatment.

• Authors: X Vandemergel, I Beukinga, P Nève
• Journal: Revue medicale de Bruxelles (Rev Med Brux) Vol. 21 Issue 3 Pg. 161-3 (Jun 2000) ISSN: 0035-3639 [Print] Belgium
• Vernacular Title: Syndrome sérotoninergique secondaire a la prise de sertraline et de métoclopramide.
• PMID: 10925598 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Antiemetics
• Drug Combinations
• Serotonin Antagonists
• Serotonin Uptake Inhibitors
• Cyproheptadine
• Metoclopramide
• Sertraline

Topics

• Adult
• Antiemetics (adverse effects)
• Cyproheptadine (therapeutic use)
• Drug Combinations
• Humans
• Male
• Metoclopramide (adverse effects)
• Serotonin Antagonists (therapeutic use)
• Serotonin Syndrome (chemically induced, drug therapy, physiopathology)
• Selective Serotonin Reuptake Inhibitors (adverse effects)
• Sertraline (adverse effects)