Abstract | AIM: METHODS: In 30 patients with suspected melanoma metastases we performed whole body imaging. After administration of about 600 MBq Tc-99m-tetrofosmin dynamic images up to 10 min were performed in 7 patients (1 image per 10 sec) to evaluate the optimal tracer uptake in the metastases. In all patients whole-body images were performed 5-10 min p.i. using an acquisition time of 5 min per image. The final diagnosis was confirmed by surgical histology in 30 lesions, by computertomography and clinical course in the remaining lesions. RESULTS: Out of 64 melanoma metastases 49 were detected using Tc-99m-tetrofosmin scintigraphy (49 rp., 15 fn.). The overall sensitivity for the detection of malignant lesions was 77%. Referring only to the lymph node metastases, the sensitivity was 87% (26 rp.; 4 fn.). The maximal tracer uptake was reached 1 min after injection, with a slow decrease in the following 10 minutes. The size of the lesions ranged between 0.5 and 7.0 cm and the T/B ratios between 1.3 and 3.0 (mean 1.88). CONCLUSIONS:
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Authors | L Rettenbacher, J Koller, H Kässmann, G Galvan |
Journal | Nuklearmedizin. Nuclear medicine
(Nuklearmedizin)
Vol. 39
Issue 4
Pg. 97-101
( 2000)
ISSN: 0029-5566 [Print] Germany |
Vernacular Title | Nachweis von Melanommetastasen mit Tc-99m-Tetrofosmin. |
PMID | 10919159
(Publication Type: Journal Article)
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Chemical References |
- Organophosphorus Compounds
- Organotechnetium Compounds
- Radiopharmaceuticals
- technetium tc-99m tetrofosmin
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Topics |
- Adult
- Aged
- Brain Neoplasms
(diagnostic imaging, secondary)
- Female
- Humans
- Lymphatic Metastasis
(diagnostic imaging)
- Male
- Melanoma
(diagnostic imaging, pathology, surgery)
- Middle Aged
- Neoplasm Metastasis
(diagnostic imaging)
- Organophosphorus Compounds
- Organotechnetium Compounds
- Radionuclide Imaging
- Radiopharmaceuticals
- Sensitivity and Specificity
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