Abstract |
Identification of patients with acute chest pain due to acute coronary syndrome is a common and difficult challenge for emergency physicians. A prospective study was conducted to assess the diagnostic value of a bedside test of cardiac troponin T in the emergency room setting. Forty-nine consecutive patients, who visited the emergency room within 6 hours of the onset of acute chest pain, were enrolled. Of the 26 patients who were ultimately diagnosed as having acute coronary syndrome, seven patients (27%) had positive cardiac troponin T assay results, whereas none of the patients without acute coronary syndrome had positive results (0%). For patients with acute coronary syndrome who presented later than 3 hours after the onset (n = 4), the test was positive in all cases (positive predictive value: 100%, negative predictive value: 100%, p < 0.01). However, the positive rate was only 14% for those who presented earlier than 3 hours after the onset (n = 22) (positive predictive value: 100%, negative predictive value: 47%, p = 0.84). In conclusion, bedside troponin T test results should be evaluated considering the time interval from the onset of chest symptoms.
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Authors | M Suzuki, S Hori, S Fujishima, S Takatsuki, I Nakamura, H Kimura, K Aoki, N Aikawa |
Journal | The Keio journal of medicine
(Keio J Med)
Vol. 49
Issue 2
Pg. 74-9
(Jun 2000)
ISSN: 0022-9717 [Print] Japan |
PMID | 10900832
(Publication Type: Comparative Study, Journal Article)
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Chemical References |
- Isoenzymes
- Troponin T
- Creatine Kinase
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Chest Pain
(blood)
- Creatine Kinase
(blood)
- Electrocardiography
- Emergency Medical Services
- Female
- Humans
- Isoenzymes
- Male
- Middle Aged
- Myocardial Infarction
(blood, diagnosis)
- Myocardium
(metabolism)
- Prospective Studies
- Troponin T
(blood)
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