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Bone marrow transplantation does not correct the hyper IgE syndrome.

Abstract
Congenital immunodeficiency in hyper IgE syndrome is characterised by a markedly raised IgE level, recurrent staphylococcal skin infection and pneumatoceles. Standard treatments include anti-staphylococcal antibiotics. We report a severely affected patient in whom successful bone marrow transplantation was followed by reappearance of the immunodeficiency. We conclude that bone marrow transplantation does not cure the immunological features of the hyper IgE syndrome. Bone Marrow Transplantation (2000) 25, 1303-1305.
AuthorsA R Gennery, T J Flood, M Abinun, A J Cant
JournalBone marrow transplantation (Bone Marrow Transplant) Vol. 25 Issue 12 Pg. 1303-5 (Jun 2000) ISSN: 0268-3369 [Print] England
PMID10871737 (Publication Type: Case Reports, Journal Article)
Topics
  • Bone Marrow Transplantation
  • Child
  • Female
  • Humans
  • Infant
  • Job Syndrome (therapy)
  • Treatment Failure

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