[A study of the clinical effect of estradiol transdermal therapeutic system alone on pollakisuria and urinary incontinence in postmenopausal woman].

Abstract

PURPOSE:

Our purpose of this study was to evaluate the effect of a transdermal estradiol delivery system in postmenopausal women with confirmed pollakisuria and urinary incontinence.

PATIENTS AND METHODS:

We investigated 10 postmenopausal women, age 54-83 years, with pollakisuria and urinary incontinence but did not show distinct urological and/or neurological abnormalities. In this study, estradiol transdermal therapeutic system (Estraderm TTS 2 mg) alone were administrated for total of 8-week and this is observational, not randomized, blinded or controlled. A clinical evaluation were performed two times at before and after administration.

RESULTS:

In seven eligible cases, the severity of urinary incontinence was graded down in almost of them and the therapeutic effect on urinary incontinence was evaluated as "very effective" in 3 cases, "improved" in 2, "slightly improved" in 1 and "no change" in 1, respectively. In three eligible cases, the severity of pollakisuria was no change in all of them.

CONCLUSION:

Thus, the estrogen supplement therapy was considered effective for postmenopausal urinary incontinence.

• Authors: S Matsumoto, T Sugiyama, T Hanai, N Ohnishi, Y C Park, T Kurita
• Journal: Nihon Hinyokika Gakkai zasshi. The japanese journal of urology (Nihon Hinyokika Gakkai Zasshi) Vol. 91 Issue 5 Pg. 501-5 (May 2000) ISSN: 0021-5287 [Print] Japan
• PMID: 10853331 (Publication Type: Clinical Trial, English Abstract, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Estradiol

Topics

• Administration, Cutaneous
• Aged
• Aged, 80 and over
• Estradiol (administration & dosage)
• Estrogen Replacement Therapy
• Female
• Humans
• Middle Aged
• Postmenopause
• Urinary Incontinence (drug therapy)