Tc-99m pertechnetate scintigraphy before and after potassium perchlorate administration for the diagnosis of retrosternal goiter.

Abstract

A 52-year-old woman was hospitalized because of dyspnea and dysphagia. Thoracic computed tomography revealed a retrotracheal mass. Tc-99m pertechnetate scintigraphy showed intense accumulation of radioactivity corresponding to the mediastinal mass detected by computed tomography. Repeated Tc-99m pertechnetate scintigraphy performed after oral administration of potassium perchlorate (KCLO4) revealed complete disappearance of the radioactive accumulation in the mediastinum, suggesting that the retrotracheal mass was a retrosternal goiter. Subsequent surgical removal and analysis of the mass showed it was indeed a retrosternal goiter. This case highlights the importance of Tc-99m pertechnetate thyroid scintigraphy with and without KCLO4 administration as a simple, accurate, and cost-effective imaging method to diagnose retrosternal goiter.

• Authors: M Aydin, S Emri, B Caner
• Journal: Clinical nuclear medicine (Clin Nucl Med) Vol. 25 Issue 6 Pg. 467-8 (Jun 2000) ISSN: 0363-9762 [Print] United States
• PMID: 10836697 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antithyroid Agents
• Perchlorates
• Potassium Compounds
• Radiopharmaceuticals
• potassium perchlorate
• Sodium Pertechnetate Tc 99m

Topics

• Administration, Oral
• Antithyroid Agents (administration & dosage, therapeutic use)
• Female
• Follow-Up Studies
• Goiter, Substernal (diagnostic imaging, drug therapy, surgery)
• Humans
• Middle Aged
• Perchlorates (administration & dosage, therapeutic use)
• Potassium Compounds (administration & dosage, therapeutic use)
• Radionuclide Imaging
• Radiopharmaceuticals
• Sodium Pertechnetate Tc 99m
• Tomography, X-Ray Computed