[++Scintimammography: a new imaging technique for diagnosis and follow-up of breast cancer].

Abstract

99m Tc MiBi has emerged as a new imaging technique for primary breast carcinomas. The aim of this study was to analyze the diagnostic performance and the additional information provided by scintimammography (SMN). Two hundred and forty consecutive women referred to surgery for abnormalities breast or suspicious breast cancer were scanned before surgery. Sensitivity and specificity were respectively 92% and 53%. PPV: 77.5% and PVN: 79.3%. All false negative scans occurred in cancers 1 cm. SMN detected multiple foci of uptake in the same breast in 13%, that were all confirmed to be multifocal disease and histology. Controlateral focal uptake was also detected; at this time 5/27 are confirmed to be bilateral breast neoplasms; 22 patients are in follow-up. SMN is reliable in the diagnosis of breast cancer and also with difficult cases of mammography. Moreover, SMN provides additional qualitative information in 19.6% of breast carcinomas, such as chest wall infiltration, multifocal or bilateral breast cancer.

• Authors: J Hermans, F Bodart, D François, P Merlo, J P Fauconnier, A Schmitz, R Gérard, D de Ruyver, L Eeckhoudt
• Journal: Bulletin du cancer (Bull Cancer) Vol. 87 Issue 4 Pg. 334-40 (Apr 2000) ISSN: 0007-4551 [Print] France
• Vernacular Title: Apport de la mammoscintigraphie 99m Tc MiBi dans le diagnostic et le suivi des cancers du sein.
• PMID: 10827352 (Publication Type: Journal Article)

Chemical References

• Radiopharmaceuticals
• Technetium Tc 99m Sestamibi

Topics

• Adenocarcinoma, Mucinous (diagnostic imaging)
• Adenofibroma (diagnostic imaging)
• Breast (diagnostic imaging)
• Breast Neoplasms (diagnostic imaging)
• Carcinoma, Ductal, Breast (diagnostic imaging)
• Feasibility Studies
• Female
• Follow-Up Studies
• Humans
• Predictive Value of Tests
• Radionuclide Imaging
• Radiopharmaceuticals
• Sclerosis (diagnostic imaging)
• Technetium Tc 99m Sestamibi