Estrogen replacement therapy and gallbladder disease in postmenopausal women.

Abstract

OBJECTIVE:

To examine the role of estrogen replacement therapy on the development of gallbladder disease in postmenopausal women.

DESIGN:

Systematic review of the English literature was conducted. All studies that addressed the association between hormone replacement therapy and gallbladder disease published from 1970 to the present were reviewed.

RESULTS:

Seven observational studies, two clinical trials, two case series, and one nonrandomized and three randomized investigations were reviewed. The results of each study were reported and analyzed.

CONCLUSIONS:

Estrogen replacement therapy in postmenopausal women increased the chances for gallstone formation.

• Authors: M L Uhler, J W Marks, H L Judd
• Journal: Menopause (New York, N.Y.) (Menopause) 2000 May-Jun Vol. 7 Issue 3 Pg. 162-7 ISSN: 1072-3714 [Print] United States
• PMID: 10810961 (Publication Type: Journal Article, Review, Systematic Review)

Chemical References

• Cholesterol

Topics

• Bile (drug effects)
• Cholelithiasis (chemistry, etiology)
• Cholesterol (analysis)
• Estrogen Replacement Therapy (adverse effects)
• Female
• Gallbladder Diseases (etiology)
• Humans
• Postmenopause
• Risk Factors