Abstract |
We describe a patient presenting with progressive bulbar dysfunction and spasticity that clinically mimicked amyotrophic lateral sclerosis (ALS). Electromyography, however, showed no evidence of denervation and revealed a rare combination of peripheral and central myokymia. We feel that this pattern of myokymia represented a marker of neural injury from remote radiation therapy. Nervous system disorders resulting from therapeutic radiation are described, and potential pathophysiologic mechanisms underlying myokymia are discussed.
|
Authors | S A Glenn, M A Ross |
Journal | Muscle & nerve
(Muscle Nerve)
Vol. 23
Issue 5
Pg. 814-7
(May 2000)
ISSN: 0148-639X [Print] United States |
PMID | 10797408
(Publication Type: Case Reports, Journal Article)
|
Copyright | Copyright 2000 John Wiley & Sons, Inc. |
Topics |
- Bulbar Palsy, Progressive
(diagnosis, etiology)
- Diagnosis, Differential
- Electromyography
- Humans
- Male
- Middle Aged
- Motor Neuron Disease
(diagnosis)
- Nasopharyngeal Neoplasms
(radiotherapy)
- Radiation Injuries
(etiology)
- Radiotherapy
(adverse effects)
|