Abstract |
We report a case of superficial undifferentiated small cell carcinoma of the esophagus. The histology of the tumor was interesting; there was squamous cell differentiation within the epithelial layer and undifferentiated small cells growing within the submucosal layer. The tumor had a negative Grimelius reaction, suggesting no differentiation into a hormone-producing carcinoma known as an apudoma ( Amine Precursor Uptake and Decarboxylation (APUD)). The serum levels of ACTH and calcitonin were within normal limits. As the patient was elderly and had a history of pleural tuberculosis causing poor pulmonary function, and owing to the fulminant nature of this carcinoma, he underwent blunt dissection of the esophagus by posterior mediastinal gastric pull-up. The patient recovered quickly and was able to be discharged with a good quality of life until the tumor recurred as a liver metastasis 6 months later.
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Authors | Y Fukunaga, S Hirata, S Tanimura, K Okawa, M Higashino, T Inoue, Y Kobayashi |
Journal | Hepato-gastroenterology
(Hepatogastroenterology)
2000 Mar-Apr
Vol. 47
Issue 32
Pg. 429-32
ISSN: 0172-6390 [Print] Greece |
PMID | 10791205
(Publication Type: Case Reports, Journal Article)
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Topics |
- Aged
- Carcinoma, Small Cell
(diagnosis, pathology, surgery)
- Cell Transformation, Neoplastic
(pathology)
- Epithelium
(pathology)
- Esophageal Neoplasms
(diagnosis, pathology, surgery)
- Esophagectomy
- Esophagoscopy
- Esophagus
(pathology)
- Humans
- Male
- Mucous Membrane
(pathology)
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