New antibiotics for gram positive infections: linezolid and combination quinapristin/dalfopristin.

Abstract

Considerable research over the past decade has thrown up two novel antibiotic preparations which are effective in 'difficult' Gram positive infections. Their imminent arrival is welcomed at a time when the emergence of resistance to last line drugs is rapidly spreading. Their careful use is, however, crucial if long-term value is to be preserved.

• Authors: A M MacConnachie
• Journal: Intensive & critical care nursing (Intensive Crit Care Nurs) Vol. 15 Issue 4 Pg. 239-41 (Aug 1999) ISSN: 0964-3397 [Print] Netherlands
• PMID: 10786510 (Publication Type: Journal Article, Review)

Chemical References

• Acetamides
• Anti-Bacterial Agents
• Anti-Infective Agents
• Oxazoles
• Oxazolidinones
• Virginiamycin
• quinupristin-dalfopristin
• Linezolid

Topics

• Acetamides (therapeutic use)
• Anti-Bacterial Agents (therapeutic use)
• Anti-Infective Agents (therapeutic use)
• Drug Prescriptions
• Drug Resistance, Microbial
• Drug Therapy, Combination (therapeutic use)
• Gram-Positive Bacterial Infections (drug therapy, epidemiology, microbiology)
• Humans
• Linezolid
• Oxazoles (therapeutic use)
• Oxazolidinones
• Safety
• Virginiamycin (therapeutic use)