Abstract | BACKGROUND: OBJECTIVE: The purpose of this study was to evaluate the impact of a nine-month weight reduction program on plasma lipids, dietary intake and abdominal fat obesity. DESIGN: A partial crossover design was used to study a weight loss treatment consisting of Phentermine hydrochloride (Fastin, SmithKline Beecham Pharmaceuticals, Philadelphia, PA) therapy plus a low energy diet (5040 kJ/d). Forty-seven obese, postmenopausal Caucasian women (BMI of 30-38 kg/m2) were randomized into two groups, both of which received drug and diet treatment over six months. However, Group I started the intervention program three months later than Group II. Plasma total, HDL and LDL cholesterol and triacylglycerol were measured, body composition was assessed by anthropometry and dual energy x-ray absorptiometry, and food frequency records were collected at four timepoints. RESULTS: CONCLUSION:
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Authors | Z R Cordero-MacIntyre, T G Lohman, J Rosen, W Peters, R C España, B Dickinson, P M Reid, W H Howell, M L Fernandez |
Journal | Journal of the American College of Nutrition
(J Am Coll Nutr)
Vol. 19
Issue 2
Pg. 275-84
(Apr 2000)
ISSN: 0731-5724 [Print] United States |
PMID | 10763910
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
- Appetite Depressants
- Cholesterol, LDL
- Lipids
- Lipoproteins
- Phentermine
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Topics |
- Adult
- Aged
- Appetite Depressants
(therapeutic use)
- Body Composition
- Body Constitution
- Body Mass Index
- Cholesterol, LDL
(blood)
- Cross-Over Studies
- Energy Intake
- Female
- Humans
- Lipids
(blood)
- Lipoproteins
(blood)
- Middle Aged
- Obesity
(blood, therapy)
- Phentermine
(therapeutic use)
- Postmenopause
- Weight Loss
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