HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Antipsychotics in the treatment of mood disorders and risk of tardive dyskinesia.

Abstract
Psychosis occurs commonly in patients with mood disorders and has traditionally been treated with typical antipsychotics. Exposure to typical antipsychotics poses a risk for the emergence of tardive dyskinesia. Atypical antipsychotics may have advantages over typical agents in the treatment of patients with mood disorders complicated by psychotic features. The studies of typical and atypical antipsychotics in the treatment of mood disorders were reviewed. Similarly, studies regarding the risk of tardive dyskinesia from typical and atypical agents in patients with mood disorders were surveyed. Typical and atypical antipsychotics appear to be comparably effective in the treatment of acute mania. Limited data regarding these medications in psychotic depression are available. Advantages of atypical antipsychotics include, for most agents, minimal extrapyramidal and prolactin effects, inherent thymoleptic activity, and lower rates of tardive dyskinesia. Atypical antipsychotics appear to have a number of advantages over typical agents in the treatment of patients with psychotic mood disorders.
AuthorsP E Keck Jr, S L McElroy, S M Strakowski, C A Soutullo
JournalThe Journal of clinical psychiatry (J Clin Psychiatry) Vol. 61 Suppl 4 Pg. 33-8 ( 2000) ISSN: 0160-6689 [Print] United States
PMID10739329 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)
Chemical References
  • Antipsychotic Agents
  • Prolactin
Topics
  • Acute Disease
  • Affective Disorders, Psychotic (blood, drug therapy)
  • Antipsychotic Agents (adverse effects, therapeutic use)
  • Basal Ganglia Diseases (blood, chemically induced, epidemiology)
  • Bipolar Disorder (blood, drug therapy, prevention & control)
  • Clinical Trials as Topic
  • Dyskinesia, Drug-Induced (epidemiology, etiology)
  • Humans
  • Hyperprolactinemia (chemically induced)
  • Multicenter Studies as Topic
  • Prolactin (blood)
  • Risk Factors

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: