[A multicenter study of the antimicrobial effect of Macmiror and Macmiror Complex in the treatment of vaginal infections].

Abstract

UNLABELLED:

The aim of the present multicentre study was to examine the therapeutic possibilities of the wide-spectrum medicament MACMIROR & MACMIROR COMPLEX for the treatment of the vaginal infections.

MATERIALS AND METHODS:

The study included 159 nonpregnant women among 15 and 54 years (middle age 35.6) with different by kind and intensity colpitis complaints. The following microbiological characteristic was established: in 26 cases Gardnerella vaginalis, in 46 Candida spp., and in the rest 87-mixed aerobic bacterial flora, with a combination of Gardnerella, yeast and Trichomonas. The treatment of the patients was done in combined scheme: peroral and vaginal administration, simultaneously with local treatment of the partner. The control examination was performed bistagely: on 7-10 day and on 30-40 day.

RESULTS:

The good clinical and microbiological influence of the treated patients was established, for the first control examination the effect was found in 88.1% and 86.8% and for the second--respectively in 81.1% and 82.4%.

CONCLUSIONS:

The received results give us a cause to approve, that the combination "Nifuratel and Nystatin" (Macmiror & Macmimor complex) has the good possibilities to influence the mixed forms of vaginal infection.

• Authors: I Karag'ozov, E Shopova, K Poriazov, I Abaliev, I Kozovski, R Ianeva, S Drenska, P Vasileva, S Bozhinova, I Popov, S Stoĭkov
• Journal: Akusherstvo i ginekologiia (Akush Ginekol (Sofiia)) Vol. 38 Issue 3 Pg. 61-2 ( 1999) ISSN: 0324-0959 [Print] Bulgaria
• Vernacular Title: Multitsentrichno prouchvane antimikrobniia efekt na Macmiror & Macmiror Complex v lechenieto na vaginalnite infektsii.
• PMID: 10734688 (Publication Type: Clinical Trial, English Abstract, Journal Article, Multicenter Study)

Chemical References

• Anti-Bacterial Agents
• Antifungal Agents
• Antitrichomonal Agents
• Drug Combinations
• Nystatin
• Nifuratel

Topics

• Adolescent
• Adult
• Anti-Bacterial Agents (therapeutic use)
• Antifungal Agents (therapeutic use)
• Antitrichomonal Agents (therapeutic use)
• Candidiasis, Vulvovaginal (drug therapy)
• Drug Combinations
• Female
• Gardnerella vaginalis
• Humans
• Middle Aged
• Nifuratel (therapeutic use)
• Nystatin (therapeutic use)
• Treatment Outcome
• Trichomonas Vaginitis (drug therapy)
• Vaginosis, Bacterial (drug therapy)