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Becaplermin gel (PDGF-BB) as topical wound therapy. Plastic Surgery Educational Foundation DATA Committee.

Abstract
Becaplermin gel is the first topical growth factor to demonstrate therapeutic efficacy in the healing of diabetic wounds. For diabetic patients who have poorly healing ulcers despite good perfusion and a reasonable trial of wound care, this product may be of considerable benefit. It should be tried for a 2-week time period and the results objectively assessed before continuation of therapy.
AuthorsD Ladin
JournalPlastic and reconstructive surgery (Plast Reconstr Surg) Vol. 105 Issue 3 Pg. 1230-1 (Mar 2000) ISSN: 0032-1052 [Print] United States
PMID10724287 (Publication Type: Journal Article)
Chemical References
  • Gels
  • Platelet-Derived Growth Factor
  • Proto-Oncogene Proteins c-sis
  • Recombinant Proteins
  • Becaplermin
Topics
  • Administration, Topical
  • Becaplermin
  • Diabetic Foot (drug therapy)
  • Gels
  • Humans
  • Platelet-Derived Growth Factor (administration & dosage)
  • Proto-Oncogene Proteins c-sis
  • Recombinant Proteins (administration & dosage)
  • Wound Healing

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