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Therapy related acute myeloid leukemia after exposure to 5-fluorouracil: a case report.

Abstract
Therapy related acute myeloid leukemia occurs after exposure to various cytotoxic agents. Among typical chemotherapeutic agents are the alkylating agents and topoisomerase II inhibitors. This type of leukemia has been reported after the use of antimetabolites. We report here a patient who developed therapy related acute myeloid leukemia secondary to the use of 5-fluorouracil.
AuthorsA Turker, N Güler
JournalHematology and cell therapy (Hematol Cell Ther) Vol. 41 Issue 5 Pg. 195-6 (Nov 1999) ISSN: 1269-3286 [Print] France
PMID10651118 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antimetabolites, Antineoplastic
  • Fluorouracil
Topics
  • Acute Disease
  • Antimetabolites, Antineoplastic (adverse effects, therapeutic use)
  • Female
  • Fluorouracil (administration & dosage, adverse effects)
  • Humans
  • Leukemia, Myeloid (etiology)
  • Middle Aged
  • Neoplasms, Second Primary
  • Stomach Neoplasms (surgery)

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