Abstract | BACKGROUND: OBJECTIVE: METHODS: A double-blind, placebo-controlled clinical study was performed in an outpatient setting in a major hospital. Ninety patients over a period of 2 years were alternatively assigned to treatment group or placebo group. Patients in the treatment group received erythromycin in divided doses for 14 days. The response was categorized as complete response, partial response, or no response. All patients were followed up for 6 weeks. RESULTS: Both groups were comparable with regard to age at presentation, sex, and average duration of disease at the time of reporting to the clinic. Upper respiratory tract infection before the appearance of skin lesions was reported in 68.8% of all patients. Complete response was observed in 33 patients (73.33%) in the treatment group and none in the placebo group (P <.0001). CONCLUSION:
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Authors | P K Sharma, T P Yadav, R K Gautam, N Taneja, L Satyanarayana |
Journal | Journal of the American Academy of Dermatology
(J Am Acad Dermatol)
Vol. 42
Issue 2 Pt 1
Pg. 241-4
(Feb 2000)
ISSN: 0190-9622 [Print] United States |
PMID | 10642679
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Anti-Bacterial Agents
- Erythromycin
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Topics |
- Administration, Oral
- Adolescent
- Adult
- Anti-Bacterial Agents
(pharmacology, therapeutic use)
- Child
- Child, Preschool
- Double-Blind Method
- Erythromycin
(pharmacology, therapeutic use)
- Female
- Humans
- Infant
- Infant, Newborn
- Male
- Pityriasis Rosea
(drug therapy, pathology)
- Treatment Outcome
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