HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Qualitative assessment of isocyanate skin exposure in auto body shops: a pilot study.

AbstractBACKGROUND:
Little is known about the extent of human isocyanate skin exposure in auto body shops and the effectiveness of personal protective equipment. Animal studies have suggested that skin exposure to isocyanates may be an important risk factor for respiratory sensitization leading to asthma. This study provides initial data on hexamethylene diisocyanate skin exposure in three auto body shops.
METHODS:
Three auto body shops of different size which use different paint systems were examined for the presence of aliphatic isocyanates on environmental surfaces and workers' skin and for breakthrough of personal protective equipment. Qualitative detection of contamination by isocyanates was conducted using a wipe-sampling technique. Assessment focused on the painters and their tasks, although other auto body repairers were also evaluated.
RESULTS:
Environmental surfaces such as painters' workbenches, spray equipment, and cleaning tools were found contaminated with isocyanates. Painters had frequent contact with contaminated surfaces, often without wearing gloves. Moderate to heavy contamination of some skin surfaces was found with painters from two of the three auto body shops. Latex gloves used for skin protection showed significant penetrations by isocyanates even after a single painting session.
CONCLUSIONS:
Contaminated environmental surfaces and skin exposure to isocyanates were documented in several auto body shops. Latex gloves were not adequate protection for workers using isocyanate paints. Further research which would better quantify skin exposure, and its potential relationship to respiratory sensitization and asthma is warranted.
AuthorsY Liu, J Sparer, S R Woskie, M R Cullen, J S Chung, C T Holm, C A Redlich
JournalAmerican journal of industrial medicine (Am J Ind Med) Vol. 37 Issue 3 Pg. 265-74 (Mar 2000) ISSN: 0271-3586 [Print] United States
PMID10642416 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
CopyrightCopyright 2000 Wiley-Liss, Inc.
Chemical References
  • Isocyanates
Topics
  • Asthma (etiology, prevention & control)
  • Automobiles
  • Dermatitis (etiology, prevention & control)
  • Dermatitis, Allergic Contact (prevention & control)
  • Humans
  • Isocyanates (adverse effects)
  • Occupational Exposure
  • Pilot Projects
  • Protective Clothing
  • Protective Devices
  • Respiratory Tract Diseases (chemically induced, immunology, prevention & control)
  • Skin (drug effects)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: