Abstract | OBJECTIVE: To analyze the available data in the literature so as to suggest a scheme for use when anticoagulating patients with ischemic vascular disease. DEVELOPMENT: CONCLUSIONS:
Anticoagulants are frequently used in cerebrovascular disease in spite of the lack of studies giving first level support of its efficacy (randomized studies with low false positive and false negative errors) and the fact that some studies have failed to confirm the efficacy of this treatment. With the analysis presented, we have tried to show that the failure to define the role of anticoagulants is mainly due to limitations in design of the methods used in the studies carried out. The basic shortcoming has been the search for one single treatment which could be effective for the entire spectrum of cerebrovascular disease.
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Authors | C J Estol |
Journal | Revista de neurologia
(Rev Neurol)
1999 Dec 1-15
Vol. 29
Issue 11
Pg. 1064-75
ISSN: 0210-0010 [Print] Spain |
Vernacular Title | Anticoagulantes: cuándo, cuál, cómo, cuánto, hasta cuándo; ésta sigue siendo la cuestión. I. |
PMID | 10637874
(Publication Type: English Abstract, Historical Article, Journal Article, Review)
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Chemical References |
- Antibodies, Antiphospholipid
- Anticoagulants
- Heparin
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Topics |
- Aged
- Antibodies, Antiphospholipid
(immunology)
- Anticoagulants
(history, therapeutic use)
- Cerebrovascular Disorders
(drug therapy, history)
- Heparin
(therapeutic use)
- History, 20th Century
- Humans
- Infusions, Intravenous
- Male
- Treatment Outcome
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