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Stimulation of nonspecific resistance by thymopentin and its analogs against Leishmania donovani infection in hamsters.

Abstract
Thymopentin and its analogs have been synthesized by the solution phase method of peptide synthesis and evaluated for their prophylactic efficacy against L. donovani infection in hamsters. Thymopentin and some of the analogs were found to stimulate nonspecific resistance of the host against Leishmania donovani infection in hamsters.
AuthorsP Sharma, Anuradha, A Rohatgi, W Haq, K B Mathur, J C Katiyar
JournalPeptides (Peptides) Vol. 20 Issue 11 Pg. 1381-3 (Nov 1999) ISSN: 0196-9781 [Print] United States
PMID10612455 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Thymopentin
Topics
  • Animals
  • Cricetinae
  • Dose-Response Relationship, Drug
  • Leishmania donovani (isolation & purification)
  • Leishmaniasis (parasitology, prevention & control)
  • Thymopentin (analogs & derivatives, therapeutic use)

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