Abstract | INTRODUCTION: There are different causes for knee joint effusions in children. Rheumatoid diseases and hematogenous septic arthritis are the most important differential diagnoses. It is less known that immunodeficiency syndromes may cause serous monarthritis. RESULTS: A case of a five years old boy with monarthritis of the knee is presented. Blood assay and specific immunologic analysis revealed a so far unknown X-linked agammaglobulinemia (M. Bruton). CONCLUSIONS: In case of a monarthritis in children the orthopaedic surgeon or the pediatrician is primarily involved. For differential diagnosis X-linked agammaglobulinemia should be considered as reason for monarthritis, especially, if there are other clues to that disease in the medical history. In the case of agammaglobulinemia effusion and swelling will decrease soon after treatment with intravenous gammaglobulin.
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Authors | J Ludwig, L Rossler |
Journal | Zeitschrift fur Orthopadie und ihre Grenzgebiete
(Z Orthop Ihre Grenzgeb)
1999 Sep-Oct
Vol. 137
Issue 5
Pg. 419-22
ISSN: 0044-3220 [Print] Germany |
Vernacular Title | Kindliche Monarthritis als Erstmanifestation einer X-gebundenen Agammaglobulinämie (M. Bruton). |
PMID | 10549119
(Publication Type: Case Reports, English Abstract, Journal Article)
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Topics |
- Agammaglobulinemia
(diagnosis, genetics)
- Arthritis
(diagnosis, genetics)
- Child, Preschool
- Diagnosis, Differential
- Genetic Linkage
(genetics)
- Humans
- Male
- Sex Chromosome Aberrations
(diagnosis, genetics)
- Tomography, X-Ray Computed
- Ultrasonography
- X Chromosome
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