Successful closure of traumatic macular holes.

Abstract

PURPOSE:

To establish the efficacy of vitreoretinal surgery without the use of transforming growth factor-beta or autologous platelet concentrate in the repair of traumatic macular holes.

METHODS:

This retrospective review consisted of 16 eyes from 16 consecutive patients treated by five vitreoretinal surgeons at a single institution between 1993 and 1997. Intervention included pars plana vitrectomy with creation of posterior vitreous detachment, placement of 14% to 16% C3F8 gas, and postoperative face-down positioning. Ten eyes received intraoperative autologous plasmin to facilitate formation of posterior vitreous detachment. Main outcome measures were anatomic closure rate and visual outcome.

RESULTS:

Anatomic closure of the macular holes was achieved in 15 (94%) of 16 eyes, with an average follow-up of 7 months. Six (38%) eyes achieved visual acuity of 20/40 or better. Visual acuity improved by 2 or more lines in 11 (69%) of 16 eyes. The average preoperative logMAR-converted visual acuity of 20/175 improved to 20/60 postoperatively.

CONCLUSION:

Traumatic macular holes can be closed successfully with substantial visual recovery without the use of transforming growth factor-beta or platelet concentrate.

• Authors: D R Chow, G A Williams, M T Trese, R R Margherio, A J Ruby, P J Ferrone
• Journal: Retina (Philadelphia, Pa.) (Retina) Vol. 19 Issue 5 Pg. 405-9 ( 1999) ISSN: 0275-004X [Print] United States
• PMID: 10546935 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Fibrinolytic Agents
• Fluorocarbons
• perflutren
• Fibrinolysin

Topics

• Adolescent
• Adult
• Child
• Eye Injuries (complications, diagnosis, surgery)
• Female
• Fibrinolysin (administration & dosage)
• Fibrinolytic Agents (administration & dosage)
• Fluorocarbons (administration & dosage)
• Follow-Up Studies
• Humans
• Injections
• Intraoperative Period
• Macula Lutea (injuries)
• Male
• Middle Aged
• Retinal Perforations (diagnosis, etiology, surgery)
• Retrospective Studies
• Treatment Outcome
• Visual Acuity
• Vitrectomy (methods)
• Vitreous Body (injuries)
• Vitreous Detachment (diagnosis, etiology, surgery)