Abstract | OBJECTIVE: DESIGN: Twenty-three NFPA post-surgical specimens were analyzed for somatostatin receptor (SSTR) expression and 12 of them were cultured in vitro to study somatostatin's effects on cell proliferation, assessed by means of [(3)H] thymidine uptake, and the intracellular signaling. RESULTS: CONCLUSIONS:
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Authors | T Florio, S Thellung, S Arena, A Corsaro, R Spaziante, G Gussoni, G Acuto, M Giusti, G Giordano, G Schettini |
Journal | European journal of endocrinology
(Eur J Endocrinol)
Vol. 141
Issue 4
Pg. 396-408
(Oct 1999)
ISSN: 0804-4643 [Print] England |
PMID | 10526255
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Calcium Channels
- Peptides, Cyclic
- lanreotide
- Somatostatin
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Topics |
- Adenoma
(drug therapy, pathology)
- Calcium Channels
(drug effects)
- Cell Division
(drug effects)
- Drug Screening Assays, Antitumor
- Female
- Humans
- Male
- Membrane Potentials
(drug effects)
- Middle Aged
- Peptides, Cyclic
(pharmacology)
- Pituitary Neoplasms
(drug therapy, pathology)
- Somatostatin
(analogs & derivatives, pharmacology)
- Tumor Cells, Cultured
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