Abstract | BACKGROUND: OBJECTIVE: METHODS: RESULTS: In addition, the methacholine concentration causing a 20% fall in FEV1 in provocation tests rose significantly, though hypersensitivity to analgesics evaluated with sulpyrine provocation testing did not decrease. These results suggest that amalgam sensitization is involved in bronchial hyperresponsiveness in aspirin-intolerant asthma. CONCLUSION: Sensitivity to amalgam may cause exacerbation of aspirin-intolerant asthma in some patients. To the best of our knowledge, this is the first case report of amalgam allergy associated with aspirin-intolerant asthma.
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Authors | S Yoshida, H Mikami, H Nakagawa, H Hasegawa, K Onuma, Y Ishizaki, T Shoji, H Amayasu |
Journal | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
(Clin Exp Allergy)
Vol. 29
Issue 10
Pg. 1412-4
(Oct 1999)
ISSN: 0954-7894 [Print] England |
PMID | 10520063
(Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Methacholine Chloride
- Dipyrone
- Dental Amalgam
- Aspirin
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Topics |
- Adult
- Aspirin
(adverse effects)
- Asthma
(diagnosis, etiology)
- Bronchial Hyperreactivity
(chemically induced, diagnosis)
- Dental Amalgam
(adverse effects)
- Dipyrone
- Female
- Humans
- Methacholine Chloride
- Skin Tests
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