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Effect of collagen implants in the reduction of high astigmatism induced by penetrating keratoplasty.

AbstractPURPOSE:
To evaluate the insertion of EagleVision collagen plugs as spacers between corneal relaxing incisions to correct significant residual astigmatism after penetrating keratoplasty (PKP).
SETTING:
Ambulatory Clinic of the Department of Ophthalmology, Rhode Island Hospital, and Rhode Island Eye Institute, Providence, Rhode Island, USA.
METHODS:
This study comprised 8 patients meeting the following criteria: had previous PKP, had at least 5.0 diopters of residual keratometric astigmatism with all the sutures removed, were free from eye infection, and were at least 21 years old. All 8 patients had unilateral high astigmatism after PKP. Four eyes were randomly assigned to the control group of astigmatic keratectomy (AK) incisions without the collagen implants and 4 eyes to the experimental group of AK incisions with collagen implants.
RESULTS:
Best corrected visual acuity 1 day, 3 weeks, and 1, 2, and 6 months after AK showed decreased astigmatism in all the patients who had the relaxing incisions. The amount of astigmatism was lower in patients who received AK incisions with collagen implants (P < .28). Minimal adverse effects were noted.
CONCLUSION:
Implanting a biocompatible material into AK incisions to correct post-PKP astigmatism appears to be safe and may enhance astigmatic correction.
AuthorsA Espaillat, K To, E M Perlman
JournalJournal of cataract and refractive surgery (J Cataract Refract Surg) Vol. 25 Issue 10 Pg. 1336-40 (Oct 1999) ISSN: 0886-3350 [Print] United States
PMID10511931 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
Chemical References
  • Biocompatible Materials
  • Collagen
Topics
  • Adult
  • Aged
  • Aged, 80 and over
  • Astigmatism (etiology, physiopathology, surgery)
  • Biocompatible Materials
  • Collagen
  • Cornea (physiopathology, surgery)
  • Female
  • Humans
  • Keratoplasty, Penetrating (adverse effects)
  • Male
  • Prostheses and Implants
  • Prosthesis Implantation
  • Treatment Outcome
  • Visual Acuity

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