Progressive confluent circumpapillary multiple evanescent white-dot syndrome.

Abstract

PURPOSE:

To describe a morphologic variant of the multiple evanescent white-dot syndrome that can mimic other conditions.

METHODS:

We examined three patients with severe cases of unilateral multiple evanescent white-dot syndrome characterized by an atypical progressive circumpapillary discoloration of the fundus.

RESULTS:

The confluent circumpapillary lesion progressed toward or beyond the equator of the fundus, raising initial concern of a viral retinitis. However, pinpoint dots at the leading edge evolved into the typical wreath-like spots of multiple evanescent white-dot syndrome, which then coalesced into the advancing edge of a geographic retinitis or retinal pigment epitheliitis, before spontaneous resolution.

CONCLUSION:

Progressive geographic circumpapillary discoloration, appearing as a giant white spot, occurs rarely in severe cases of multiple evanescent white-dot syndrome. The distinctive appearance may suggest a disorder other than multiple evanescent white-dot syndrome, which can make initial diagnosis more difficult and lead to unnecessary or inappropriate testing and treatment.

• Authors: J K Luttrull, M F Marmor, M Nanda
• Journal: American journal of ophthalmology (Am J Ophthalmol) Vol. 128 Issue 3 Pg. 378-80 (Sep 1999) ISSN: 0002-9394 [Print] United States
• PMID: 10511044 (Publication Type: Case Reports, Journal Article)

Topics

• Adult
• Disease Progression
• Female
• Fluorescein Angiography
• Fundus Oculi
• Humans
• Male
• Optic Disk (pathology)
• Retinal Diseases (diagnosis)
• Syndrome
• Visual Acuity