[Functional activity of hemagglutinins from Hantaan viruses strains and use of hemagglutinating antigens for serodiagnosis hemorrhagic fever with kidney syndrome].

Abstract

Hemagglutinins of Hantaan virus strains isolated in Southern Far East of Russia from patients with hemorrhagic fever with the renal syndrome and from rodents, natural vectors of the virus, were studied in the cross kinetic hemagglutination inhibition test with immune sera to the studied strains. The strains differed by the functional activity index. Use of hemagglutinins of functionally active Hantaan strains in serologic studies notably improves the diagnostic efficacy of the hemagglutination test in Hantavirus infection.

• Authors: T V Kushnareva, R A Slonova, G G Kompanets, T I Astakhova
• Journal: Voprosy virusologii (Vopr Virusol) 1999 Jul-Aug Vol. 44 Issue 4 Pg. 186-90 ISSN: 0507-4088 [Print] Russia (Federation)
• Vernacular Title: Funktsional'naia aktivnost' gemaggliutininov shtammov virusa Khantaan i ispol'zovanie gemaggliutiniruiushchikh antigenov dlia serodiagnostiki gemorrhagicheskoĭ likhoradki s pochechnym sindromom.
• PMID: 10500991 (Publication Type: English Abstract, Journal Article)

Chemical References

• Antigens, Viral
• Hemagglutinins, Viral

Topics

• Animals
• Antigens, Viral
• Arvicolinae
• Disease Vectors
• Hantaan virus (metabolism)
• Hemagglutinins, Viral (metabolism)
• Hemorrhagic Fever with Renal Syndrome (diagnosis)
• Humans
• Mice