[Immunology of tuberculosis: current status].

Abstract

The paper outlines the high-priority trends in basic and applied investigations of antituberculous immunity. It presents the results obtained from studies of the genetic mechanisms responsible for the control of susceptibility in experimental tuberculosis, from analyses of novel chemical and recombinant tuberculosis vaccines, from examinations of the role of immunological memory in the disease. While describing the results of tuberculosis immunodiagnosis, particular emphasis is laid on its major aspects: on the differential diagnosis of tuberculosis and other lung diseases and on the screening of high-risk group populations for disease progression in order to made further in-depth studies. Current aspects of evaluating the immune status and nonspecific responsiveness in patients with tuberculosis are considered.

• Authors: V I Litvinov, V Ia Gergert, A M Moroz, A S Apt, V V Eremeev, G A Kosmiadi, N V Kulikovskaia, I V Liadova, B V Nikoneko
• Journal: Vestnik Rossiiskoi akademii meditsinskikh nauk (Vestn Ross Akad Med Nauk) Issue 7 Pg. 8-11 ( 1999) ISSN: 0869-6047 [Print] Russia (Federation)
• Vernacular Title: Immunologiia tuberkuleza: sovremennoe sostoianie problemy.
• PMID: 10467877 (Publication Type: English Abstract, Journal Article, Review)

Chemical References

• Adjuvants, Immunologic
• Antitubercular Agents
• BCG Vaccine

Topics

• Adjuvants, Immunologic (therapeutic use)
• Animals
• Antitubercular Agents (therapeutic use)
• BCG Vaccine (therapeutic use)
• Diagnosis, Differential
• Humans
• Immunity
• Immunologic Tests
• Tuberculosis, Pulmonary (diagnosis, immunology, prevention & control)