Management of labor in Eisenmenger syndrome with inhaled nitric oxide.

Abstract

Administration of nitric oxide by means of inhalation during the labor of a woman with Eisenmenger's syndrome caused by an atrial septal defect resulted in improved oxygenation and initial pulmonary arterial pressure. She gave birth to a live infant at 34 weeks' gestation but died of worsening pulmonary hypertension and heart failure 21 days post partum.

• Authors: K M Lust, R J Boots, M Dooris, J Wilson
• Journal: American journal of obstetrics and gynecology (Am J Obstet Gynecol) Vol. 181 Issue 2 Pg. 419-23 (Aug 1999) ISSN: 0002-9378 [Print] United States
• PMID: 10454694 (Publication Type: Case Reports, Journal Article)

Chemical References

• Nitric Oxide
• Oxytocin
• Heparin
• Oxygen

Topics

• Administration, Inhalation
• Adult
• Bed Rest
• Eisenmenger Complex (complications, therapy)
• Female
• Gestational Age
• Heparin (therapeutic use)
• Humans
• Labor, Obstetric
• Nitric Oxide (administration & dosage, therapeutic use)
• Oxygen (administration & dosage)
• Oxytocin (therapeutic use)
• Postpartum Hemorrhage (drug therapy)
• Pregnancy
• Pregnancy Complications, Cardiovascular (therapy)