[Reasons for fresh frozen plasma transfusion in a general hospital].

Abstract

OBJECTIVE:

To assess the fresh-frozen plasma (FFP) transfusion indications in a Mexican hospital.

SETTING:

A general hospital for federal government employees located in the city of Morelia, State of Michoacan, Mexico.

MATERIAL AND METHODS:

We evaluated all FFP transfusions between February and August, 1998 classifying them as appropriate or inappropriate according to the recent FFP-transfusion guidelines: correction of known coagulation factor deficiencies with bleeding and correction of microvascular bleeding when prothrombin and activated partial thromboplastin time are > 1.6 times normal (coagulation index o CI), urgent reversal of warfarin therapy, antithrombin III deficiency, thrombotic thrombocytopenic purpura treatment, liver transplant and acute disseminated intravascular coagulation.

RESULTS:

78 patients with 292 FFP units transfused were analyzed: in 20 patients the indication was clotting support, 16 with CI < 1.5 and four with CI > 1.6, one with blood loss and one with surgical procedure; hypoalbuminemia in 10; hypovolemia in eight; unidentified reason in 33 and others in seven patients. Eleven units (3.76%) were considered properly transfused whereas 281 (96.23%) were inadequately indicated.

• Authors: L Pita-Ramírez, B E Cabrera Carbajal, C Ortega Zavala
• Journal: Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion (Rev Invest Clin) 1999 Mar-Apr Vol. 51 Issue 2 Pg. 89-92 ISSN: 0034-8376 [Print] Mexico
• Vernacular Title: Motivos de transfusión de plasma fresco congelado en un hospital general.
• PMID: 10410587 (Publication Type: Journal Article)

Chemical References

• Anticoagulants
• Warfarin

Topics

• Anticoagulants (adverse effects)
• Blood Coagulation Disorders (therapy)
• Blood Coagulation Tests
• Blood Component Transfusion (adverse effects, statistics & numerical data)
• Blood Loss, Surgical
• Disseminated Intravascular Coagulation (therapy)
• Hemorrhage (therapy)
• Hospitals, General (statistics & numerical data)
• Humans
• Liver Transplantation
• Medical Audit
• Mexico
• Plasma
• Preoperative Care
• Purpura, Thrombotic Thrombocytopenic (therapy)
• Warfarin (adverse effects)