[Lipoprotein profile of patients infected with HIV in Côte d'Ivoire].

Abstract

Aids is a cachexysing disease which is striking Africa. Côte d'Ivoire with its 12% seroprevalence is paying a heavy tribute to this pandemia. The course of the disease is characterized by the occurrence of immunological and biochemical disorders. The aim of this study is to offer African practitioners, clinicians and biologists some biochimical parameters that would help them to follow up people infected with HIV. The authors determined the lipoprotein profile in 204 people (112 Aids patients, 61 HIV infected asymptomatics and 31 controls seronegative to HIV), of both sexes aged 17 to 70 years old. The results show a relatively high level of triglyceridemia, a decreased level of total cholesterol, apoproteins A1 and B and a hypergammaglobulinemia with concomitant and significant increase in the level of orosomucoide as a stigmate of inflammation. These data could help practitioners who lack CD4/CD8 count and viral load monitoring in the follow up of their AIDS patients.

• Authors: P Djessou, A R Kakou, C M Camara, M N'ko, G Tiahou, A F Mansour, E Bissagnene, E D Sess
• Journal: Bulletin de la Societe de pathologie exotique (1990) (Bull Soc Pathol Exot) Vol. 92 Issue 2 Pg. 107-8 (May 1999) ISSN: 0037-9085 [Print] France
• Vernacular Title: Etude du profil lipidoprotéinique des sujets infectés par le VIH en Côte d'Ivoire.
• PMID: 10399600 (Publication Type: English Abstract, Journal Article)

Chemical References

• Apolipoprotein A-I
• Apolipoproteins B
• Immunoglobulins
• Lipoproteins
• Orosomucoid
• Triglycerides
• Cholesterol

Topics

• Acquired Immunodeficiency Syndrome (blood)
• Adolescent
• Adult
• Apolipoprotein A-I (blood)
• Apolipoproteins B (blood)
• Cholesterol (blood)
• Cote d'Ivoire
• Female
• HIV Infections (blood)
• Humans
• Hypergammaglobulinemia (blood)
• Immunoglobulins (blood)
• Lipoproteins (blood)
• Male
• Middle Aged
• Orosomucoid (analysis)
• Triglycerides (blood)