Abstract | BACKGROUND: METHODS: RESULTS: Statistical evaluation revealed that all clinical variables showed statistical decreases compared to baseline in the treated patients, while none of the parameters changed significantly in the control group. Initial GH scores of 53.63% in controls and 53.40% in the treated patients were 52.83% and 32.13% following treatment, respectively. A difference of 21.27% in the severity of treated GH was accompanied by a 0.56 decrease in GI scores in the test group. CONCLUSIONS: Compared to the initial observations, the results suggested that nearly 60% of the condition could be of fibrotic origin. Initial periodontal therapy and curettage resulted in the resolution of the inflammation in CsA-induced GH. Further investigation of the treated patients has shown that 7 out of 15 patients (47%) in the test group responded well and their GH scores decreased below 30% at the end of the study. The treatment in this study was effective in eliminating the necessity of more extensive surgical modes of treatment, such as gingivectomy, in 47% of cases.
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Authors | A Kantarci, I Cebeci, O Tuncer, M Carin, E Firatli |
Journal | Journal of periodontology
(J Periodontol)
Vol. 70
Issue 6
Pg. 587-93
(Jun 1999)
ISSN: 0022-3492 [Print] United States |
PMID | 10397513
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Immunosuppressive Agents
- Cyclosporine
|
Topics |
- Adult
- Cyclosporine
(adverse effects)
- Dental Care for Chronically Ill
- Dental Scaling
- Female
- Gingival Hyperplasia
(chemically induced, complications, pathology, therapy)
- Gingivitis
(etiology, therapy)
- Humans
- Immunosuppressive Agents
(adverse effects)
- Kidney Transplantation
- Male
- Oral Hygiene
(education)
- Periodontal Index
- Subgingival Curettage
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