HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Ingestion of low-concentration hydrofluoric acid: an insidious and potentially fatal poisoning.

AbstractSTUDY OBJECTIVE:
The purpose of this study was to provide the first description of the effects of ingestion of low-concentration hydrofluoric acid in a population reported to a regional poison control center.
METHODS:
A retrospective analysis of data collected by trained personnel using a standardized data collection system was performed. All charts involving hydrofluoric acid exposures for a 2-year period from a certified regional poison control center were identified by a computerized search. Each chart was abstracted by trained and blinded personnel.
RESULTS:
There were 1,772 exposures to hydrofluoric acid; 135 involved ingestion. There were 99 cases of human hydrofluoric acid ingestion for analysis. All ingestions involved consumer products containing 6% to 8% hydrofluoric acid. Symptoms, most commonly mild gastrointestinal effects, were reported by 49 patients. Two patients with minimal effects during an observation period of 2 to 4 hours deteriorated suddenly and died. All other patients recovered completely. Of 29 cases in which calcium concentrations were recorded, 4 cases of hypocalcemia occurred. All patients who had major effects or died were adults who had ingested more than 3 ounces of hydrofluoric acid with suicidal intent. Death occurred precipitously in patients who had appeared well a few minutes earlier.
CONCLUSION:
Death occurred in 2 patients, both of whom were adults who had ingested more than 3 ounces with suicidal intent. Ingestion of a household product containing hydrofluoric acid is a potentially life-threatening condition that requires close monitoring and prompt therapy. The abrupt deterioration and lack of warning signs indicate the need for better diagnostic methods.
AuthorsW F Kao, R C Dart, E Kuffner, G Bogdan
JournalAnnals of emergency medicine (Ann Emerg Med) Vol. 34 Issue 1 Pg. 35-41 (Jul 1999) ISSN: 0196-0644 [Print] United States
PMID10381992 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Hydrofluoric Acid
Topics
  • Adult
  • Age Distribution
  • Animals
  • Child
  • Emergency Treatment (methods)
  • Female
  • Humans
  • Hydrofluoric Acid (poisoning)
  • Hypocalcemia (etiology)
  • Male
  • Poison Control Centers
  • Poisoning (complications, diagnosis, epidemiology, therapy)
  • Population Surveillance
  • Regional Medical Programs
  • Retrospective Studies
  • Sex Distribution
  • Single-Blind Method
  • Suicide (statistics & numerical data)
  • Time Factors
  • Treatment Outcome

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: