Cogan's syndrome with refractory abdominal aortitis and mesenteric vasculitis.

Abstract

Cogan's syndrome is a rare multisystem disease characterized by ocular inflammation, vestibuloauditory dysfunction, and vasculitis. We report a 26-year-old Caucasian woman who died from Cogan's syndrome. Her case illustrates that patients with Cogan's syndrome can have abdominal aortitis and mesenteric vasculitis, and that the vasculitis can be refractory to methotrexate, cyclophosphamide, cyclosporine, and chlorambucil.

• Authors: A C Ho, M I Roat, A Venbrux, D B Hellmann
• Journal: The Journal of rheumatology (J Rheumatol) Vol. 26 Issue 6 Pg. 1404-7 (Jun 1999) ISSN: 0315-162X [Print] Canada
• PMID: 10381065 (Publication Type: Case Reports, Journal Article)

Chemical References

• Immunosuppressive Agents

Topics

• Adult
• Aortitis (complications, drug therapy)
• Fatal Outcome
• Female
• Hearing Loss, Sensorineural (complications)
• Hearing Loss, Sudden (complications)
• Humans
• Immunosuppressive Agents (therapeutic use)
• Keratitis (complications, drug therapy)
• Mesentery (blood supply)
• Syndrome
• Vasculitis (complications, drug therapy)
• Vertigo (complications)