Abstract | PURPOSE: To compare cardiac muscle cells width and cardiomyocyte lipofuscin pigment presence between malnourished and non-malnourished necropsied adults. METHODS: RESULTS: Malnourished (n = 8) and controls (n = 4), respectively, showed statistical differences in relation to BMI (14.86 +/- 1.13 vs 22.02 +/- 0.9 kg/m2), heart weight/body weight ratio (0.68 +/- 0.09 vs 0.54 +/- 0.07%), cardiomyocytes width (10.91 +/- 0.77 vs 12.90 +/- 1.82 microns) and lipofuscin pigment presence (39.1 vs 54.4%). CONCLUSION: When compared with controls, necropsied malnourished adults showed decreased myocardial fibers diameters and lower lipofuscin pigment presence. These findings might reflect altered metabolism, and would be associated with harmful clinical effects in terminally ill patients.
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Authors | D F da Cunha, C H Pedrini, J C Sousa, M A dos Reis, S G Ramos, S F da Cunha, V de P Teixeira |
Journal | Arquivos brasileiros de cardiologia
(Arq Bras Cardiol)
Vol. 71
Issue 5
Pg. 677-80
(Nov 1998)
ISSN: 0066-782X [Print] Brazil |
Vernacular Title | Estudo morfométrico do miocárdio em adultos com subnutrição protéico-energética. |
PMID | 10347950
(Publication Type: Comparative Study, English Abstract, Journal Article)
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Chemical References |
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Topics |
- Adult
- Body Mass Index
- Case-Control Studies
- Female
- Humans
- Lipofuscin
(analysis)
- Male
- Myocardium
(pathology)
- Nutritional Status
- Protein-Energy Malnutrition
(complications, pathology)
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