[A study on efficacy of rabies vaccine prepared by primary hamster kidney cells in Guangxi].

Abstract

OBJECTIVE:

To study the efficacy of post-exposure use of concentrated rabies vaccine prepared by primary hamster kidney cells during the past 16 years (1980-1995) in the Guangxi Zhuang Autonomous Region and the role of ambulant care for the victims injured by dog-bite.

METHODS:

Data of rabies incidence notified from all the prefectures and cities in Guangxi were summarized and corroborated, field studies were conducted and rabies antibodies were determined.

RESULTS:

Incidence of rabies fell to 0.04 per ten thousand in 1995 from 2.46 per ten thousand in 1981 with increased use of post-exposure rabies immunization with concentrated vaccine and in-time treatment for dog-bite wounds in the widespread ambulant care settings.

CONCLUSION:

Rabies vaccine prepared by primary hamster kidney cells has good efficacy in protection from rabies and early and in-time treatment for dog-bite wounds could enhance their protective effects. It is suggested that concentrated vaccine be purified to avoid adverse effects caused by its allergen.

• Authors: T Wu, Y Lu, X Ge
• Journal: Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] (Zhonghua Yu Fang Yi Xue Za Zhi) Vol. 32 Issue 4 Pg. 211-3 (Jul 1998) ISSN: 0253-9624 [Print] China
• PMID: 10322757 (Publication Type: English Abstract, Journal Article)

Chemical References

• Antibodies, Viral
• Rabies Vaccines

Topics

• Animals
• Antibodies, Viral (blood)
• China (epidemiology)
• Cricetinae
• Humans
• Incidence
• Kidney (cytology)
• Mice
• Rabies (epidemiology, prevention & control)
• Rabies Vaccines (immunology)
• Rabies virus (immunology)