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Carcinoembryonic antigen in patients with untreated central nervous system tumors.

Abstract
This study was designed to determine whether immunological examination of carcinoembryonic antigen (CEA) levels in blood serum and cerebrospinal fluid would be helpful in detecting central nervous system tumors. Forty patients with tumors of the central nervous system were compared with 108 control patients. The findings suggest that: 1) CEA determinations are not helpful as a screening test in detecting preclinical central nervous system tumors; 2) Serum CEA determinations may be useful in determining the presence of a malignant tumor in patients with a circumscribed uptake on brain scan or a nonspecific mass lesion at cerebral angiography; 3) Cerebrospinal fluid CEA determinations were of no value in detecting central nervous system tumors; 4) Further study on a larger population of malignant central nervous system tumors is warranted.
AuthorsD K Kido, B J Dyce, B J Haverback, C L Rumbaugh
JournalBulletin of the Los Angeles neurological societies (Bull Los Angeles Neurol Soc) Vol. 41 Issue 2 Pg. 47-54 (Apr 1976) ISSN: 0024-659X [Print] United States
PMID1030651 (Publication Type: Journal Article)
Chemical References
  • Carcinoembryonic Antigen
Topics
  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Alcohol Drinking
  • Brain Neoplasms (diagnosis)
  • Carcinoembryonic Antigen (analysis, cerebrospinal fluid)
  • Child
  • False Positive Reactions
  • Female
  • Humans
  • Male
  • Middle Aged
  • Smoking

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