Recurrence of desmoid tumor in a multivisceral transplant patient with Gardner's syndrome.

Abstract

BACKGROUND:

Desmoid tumors are locally invasive fibromatous tumors, which, in patients with Gardner's syndrome, usually occur in the abdominal wall or intra-abdominally. After excision, they tend to recur, often leading to multiple bowel resections.

METHODS:

This is a report of the clinical course of a patient with Gardner's syndrome and desmoid tumor who had multiple enterectomies and gradually developed short-gut syndrome. He required prolonged parenteral nutrition, which damaged the liver. The patient underwent a multivisceral transplantation as a life-saving procedure.

RESULTS:

After the transplant, the desmoid tumor recurred in the thoracic wall twice and was successfully resected. It also recurred in the abdominal cavity, compressing the intestinal loops; the tumor was excised uneventfully, leaving the graft intact. The recurrent tumors were all of recipient origin.

CONCLUSIONS:

Intestinal and multivisceral transplantation could be considered in patients with short-gut syndrome caused by recurrent desmoid tumor. In the case of posttransplant tumor recurrence, resection is the only option recommended.

• Authors: E P Misiakos, A Pinna, T Kato, M G Rodriguez, A Francavilla, V Mazzaferro, P Ruiz, J D Reith, A G Tzakis
• Journal: Transplantation (Transplantation) Vol. 67 Issue 8 Pg. 1197-9 (Apr 27 1999) ISSN: 0041-1337 [Print] United States
• PMID: 10232576 (Publication Type: Case Reports, Journal Article)

Topics

• Adult
• Gardner Syndrome (surgery)
• Humans
• Male
• Neoplasm Recurrence, Local (diagnostic imaging, surgery)
• Reoperation
• Tomography, X-Ray Computed
• Viscera (transplantation)