Abstract |
Fifty-three patients with carcinomas of the head and neck with N2 or N3 metastatic cervical lymph nodes were treated with radiation therapy (median, 70 Gy), cisplatin (median, 6 weekly courses) and hyperthermia (median, 6 twice weekly sessions). Local complete response was achieved in 82% and nodal complete response in 85% of patients. Overall survival was 51% and disease-free survival was 54% at 2 years. Toxicity was acceptable. Radiation therapy, cisplatin and hyperthermia in combination prove to be effective and safe in management of these patients.
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Authors | M Serin, H S Erkal, A Cakmak |
Journal | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
(Radiother Oncol)
Vol. 50
Issue 1
Pg. 103-6
(Jan 1999)
ISSN: 0167-8140 [Print] Ireland |
PMID | 10225563
(Publication Type: Journal Article)
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Chemical References |
- Antineoplastic Agents
- Cobalt Radioisotopes
- Radiopharmaceuticals
- Cisplatin
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Topics |
- Adolescent
- Adult
- Aged
- Antineoplastic Agents
(adverse effects, therapeutic use)
- Carcinoma
(drug therapy, radiotherapy, secondary, therapy)
- Cisplatin
(adverse effects, therapeutic use)
- Cobalt Radioisotopes
(adverse effects, therapeutic use)
- Combined Modality Therapy
- Disease-Free Survival
- Female
- Follow-Up Studies
- Head and Neck Neoplasms
(drug therapy, radiotherapy, therapy)
- Humans
- Hyperthermia, Induced
(adverse effects)
- Lymphatic Metastasis
(pathology, radiotherapy)
- Male
- Middle Aged
- Neck
- Prospective Studies
- Radiopharmaceuticals
(adverse effects, therapeutic use)
- Radiotherapy Dosage
- Remission Induction
- Survival Rate
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