[Use of gabapentin in glossopharyngeal neuralgia].

Abstract

Anticonvulsant drugs, especially carbamazepine, are the treatment of choice for glossopharyngeal neuralgia. If no clinical response is obtained, surgical treatment, including nerve section or decompression, may be required. We report the results obtained with a new anticonvulsant, gabapentin, as an alternative for cases of carbamazepine failure. In 7 patients with bouts of glosso-pharyngeal neuralgia refractory to the usual medical treatment, gabapentin produced improvement in 5 patients. Response was poor in patients who had undergone surgical nerve decompression. Gabapentin was concluded to be an effective therapeutic option for neuralgia of the IXth cranial nerve before surgery.

• Authors: F J García Callejo, J Marco Algarra, F Talamantes Escribá, M P Martínez Beneyto, M Esparcia Navarro, A Morant Ventura
• Journal: Acta otorrinolaringologica espanola (Acta Otorrinolaringol Esp) Vol. 50 Issue 2 Pg. 175-7 (Mar 1999) ISSN: 0001-6519 [Print] Spain
• Vernacular Title: Empleo de gabapentina en la neuralgia del glosofaríngeo.
• PMID: 10217696 (Publication Type: Journal Article)

Chemical References

• Acetates
• Amines
• Analgesics
• Cyclohexanecarboxylic Acids
• gamma-Aminobutyric Acid
• Gabapentin

Topics

• Acetates (therapeutic use)
• Adult
• Amines
• Analgesics (therapeutic use)
• Cyclohexanecarboxylic Acids
• Female
• Gabapentin
• Glossopharyngeal Nerve (physiopathology)
• Humans
• Male
• Middle Aged
• Neuralgia (drug therapy, physiopathology)
• Treatment Outcome
• gamma-Aminobutyric Acid