Atypical mycobacterium infection with dermatological manifestation in a renal transplant recipient.

Abstract

In April 1997, a 58-year-old renal transplant recipient presented with abscess-like nodules in his left calf and on his right foot. Furuncular disease was suspected and the patient was treated with flucloxacillin. However, the lesions increased in size and became ulcerative. In the following 3 months, cultures of punctuated material, blood, and urine remained negative and gram stains did not reveal micro-organisms. In June 1997, acid-fast stains were positive. A diagnosis of a nontuberculous mycobacterium (NTM) infection was made and empirical antimycobacterial therapy was started. The combination of relatively minor symptoms with enlarged purulent lesions, causing severe morbidity, raises the possibility of NTM infection in the immunocompromised patient.

• Authors: J J de Jong, T van Gelder, J N IJzermans, H P Endtz, W Weimar
• Journal: Transplant international : official journal of the European Society for Organ Transplantation (Transpl Int) Vol. 12 Issue 1 Pg. 71-3 ( 1999) ISSN: 0934-0874 [Print] Switzerland
• PMID: 10080410 (Publication Type: Case Reports, Journal Article)

Chemical References

• Ethambutol
• Ofloxacin
• Clarithromycin
• Rifampin

Topics

• Clarithromycin (therapeutic use)
• Drug Therapy, Combination (therapeutic use)
• Ethambutol (therapeutic use)
• Foot
• Humans
• Kidney Transplantation
• Male
• Middle Aged
• Mycobacterium Infections, Nontuberculous (diagnosis, drug therapy)
• Nontuberculous Mycobacteria (classification, isolation & purification)
• Ofloxacin (therapeutic use)
• Postoperative Complications
• Rifampin (therapeutic use)
• Skin Diseases, Bacterial (diagnosis, drug therapy)