Effectiveness of fundoplication in early infancy.

Abstract

PURPOSE:

The aim of this study was to evaluate the results of fundoplication performed in the first 4 months of life.

METHODS:

Case-notes of 66 patients less than 4 months old who underwent fundoplication between January 1986 and July 1997 were reviewed. The mean length of follow-up was 24 months (range, 3 to 115 months). Diagnosis of gastrooesophageal reflux (GOR) was based on a barium meal in 55 patients or 24-hour pH monitoring in 23 patients.

RESULTS:

Fundoplication was performed at a median age of 9 weeks (range, 3 to 15 weeks). Associated anomalies were identified in 56 infants and included oesophageal atresia or tracheooesophageal fistula (n = 19), lung abnormalities (n = 7), congenital diaphragmatic hernia (n = 4), and various other complex syndromes including neurological disorders (n = 26). Isolated GOR occurred in 10. Ninety percent of infants with isolated GOR improved clinically after the fundoplication compared with 64% of those with associated anomalies. Only 58% of infants in whom GOR developed after oesophageal atresia repair improved after fundoplication. Vomiting was reduced after fundoplication in 76% of infants, apnoea and/or respiratory symptoms improved in 66%, whereas failure to thrive incidence improved in only 38% of infants. Revision of the fundoplication was required in 16 (24%) patients. There were eight deaths, all of which occurred at least 6 months after the fundoplication.

CONCLUSIONS:

Fundoplication in early infancy is unsuccessful in a high proportion of patients. The highest incidence of failure and redo fundoplication occurred in infants with associated anomalies. The best results were achieved in infants with emesis and respiratory symptoms.

• Authors: R Kubiak, L Spitz, E M Kiely, D Drake, A Pierro
• Journal: Journal of pediatric surgery (J Pediatr Surg) Vol. 34 Issue 2 Pg. 295-9 (Feb 1999) ISSN: 0022-3468 [Print] United States
• PMID: 10052808 (Publication Type: Journal Article)

Topics

• Female
• Follow-Up Studies
• Fundoplication (methods)
• Gastroesophageal Reflux (complications, diagnosis, surgery)
• Humans
• Hydrogen-Ion Concentration
• Infant
• Infant, Newborn
• Male
• Monitoring, Physiologic
• Treatment Outcome