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Inflammatory Breast Neoplasms

Metastatic breast cancer characterized by EDEMA and ERYTHEMA of the affected breast due to LYMPHATIC METASTASIS and eventual obstruction of LYMPHATIC VESSELS by the cancer cells.
Also Known As:
Inflammatory Breast Cancer (IBC); Inflammatory Breast Carcinoma; Breast Cancer, Inflammatory; Breast Cancers, Inflammatory; Breast Carcinoma, Inflammatory; Breast Carcinomas, Inflammatory; Breast Neoplasm, Inflammatory; Breast Neoplasms, Inflammatory; Cancer, Inflammatory Breast; Cancers, Inflammatory Breast; Carcinoma, Inflammatory Breast; Carcinomas, Inflammatory Breast; Inflammatory Breast Cancers; Inflammatory Breast Carcinomas; Inflammatory Breast Neoplasm; Neoplasm, Inflammatory Breast; Neoplasms, Inflammatory Breast; Inflammatory Breast Cancer
Networked: 794 relevant articles (53 outcomes, 123 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Breast Neoplasms (Breast Cancer)
2. Neoplasms (Cancer)
3. Non-Hodgkin Lymphoma (Lymphosarcoma)
4. Small Cell Lung Carcinoma (Small Cell Lung Cancer)
5. Neoplasm Metastasis (Metastasis)

Experts

1. Ueno, Naoto T: 54 articles (10/2021 - 02/2008)
2. Woodward, Wendy A: 44 articles (06/2022 - 07/2007)
3. Cristofanilli, Massimo: 41 articles (06/2022 - 01/2003)
4. Lucci, Anthony: 27 articles (05/2022 - 12/2003)
5. Valero, Vicente: 20 articles (12/2021 - 08/2005)
6. Bertucci, François: 20 articles (10/2021 - 12/2004)
7. Krishnamurthy, Savitri: 19 articles (10/2021 - 11/2009)
8. Gong, Yun: 19 articles (01/2021 - 10/2006)
9. Buchholz, Thomas A: 17 articles (11/2019 - 01/2002)
10. Hortobagyi, Gabriel N: 16 articles (10/2021 - 01/2003)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Inflammatory Breast Neoplasms:
1. Paclitaxel (Taxol)FDA LinkGeneric
2. Lapatinib (GW572016)FDA Link
3. Granulocyte Colony-Stimulating Factor (G-CSF)IBA
02/01/2000 - "High-dose sequential chemotherapy with recombinant granulocyte colony-stimulating factor and repeated stem-cell support for inflammatory breast cancer patients: does impact on quality of life jeopardize feasibility and acceptability of treatment?"
11/01/2017 - "[A Case of Rapidly Advancing G-CSF Producing Pleomorphic Carcinoma of the Breast Appearing as an Inflammatory Breast Cancer]."
04/01/2001 - "A total of 47 G-CSF mobilized stem cell grafts from patients with nodal-positive (n = 30), chemosensitive metastatic (n = 11), and 5 women with inflammatory breast cancer were evaluated for cancer cells by immunocytochemistry. "
02/01/2000 - "This study was designed to investigate the quality of life (QOL) of patients enrolled onto the High-Dose Chemotherapy for Breast Cancer Study Group trial (PEGASE 02), a French pilot multicenter trial of the treatment of inflammatory breast cancer (IBC) aimed at evaluating (1) toxicity and feasibility of sequential high-dose chemotherapy (HDC) with recombinant human granulocyte colony-stimulating factor (filgrastim) and stem-cell support and (2) response to HDC in terms of pathologic response and survival. "
01/01/1994 - "To evaluate the safety and efficacy of lenograstim, a new recombinant human granulocyte colony-stimulating factor (rHuG-CSF), as an adjunct to cancer chemotherapy, 3 phase III randomised clinical trials were recently conducted in Europe in patients with inflammatory breast cancer, non-Hodgkin's lymphoma, and small cell lung cancer. "
4. LenograstimIBA
5. Trastuzumab (Herceptin)FDA Link
6. AnthracyclinesIBA
7. Epirubicin (Ellence)FDA LinkGeneric
8. Cyclophosphamide (Cytoxan)FDA LinkGeneric
9. Doxorubicin (Adriamycin)FDA LinkGeneric
10. Bevacizumab (Avastin)FDA Link

Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Therapeutics
3. Neoadjuvant Therapy
4. Radiotherapy
5. Mastectomy (Mammectomy)