Purinergic P1 Receptor Agonists

05/01/1996 - "[The effect of adenosine receptor agonists on the normal cerebral blood flow and in subsequent ischemia]."
05/01/2010 - "We now studied the effects of adenosine receptor agonists and antagonists on [(3)H]taurine release in the brain stem in normoxia and ischemia, using a superfusion system. "
05/01/2010 - "Adenosine receptor agonists affect taurine release from mouse brain stem slices in ischemia."
05/01/2009 - "Extracellular adenosine concentrations increase within the heart during ischemia, and any exogenous adenosine receptor agonists therefore work in the context of significant local agonist concentrations. "
06/01/1995 - "In the heart, adenosine, A1 adenosine receptor agonists, and a brief period of preconditioning ischemia attenuate I-R injury. "

08/01/2008 - "A2A adenosine receptor agonists for the treatment of asthma?"
03/01/2001 - "Therapy of bronchial asthma with adenosine receptor agonists or antagonists."
01/01/2018 - "Inhaled adenosine receptor agonists induce bronchoconstriction and inflammation in asthma and are used as bronchial challenge agents for the diagnosis of asthma and in respiratory drug development. "
03/01/2000 - "Based on these results, highly selective A(3) adenosine receptor agonists and/or antagonists have been indicated as potential drugs for the treatment of asthma and inflammation, while highly selective agonists have been shown to possess cardioprotective effects. "
01/01/2018 - "The aim of the current study was to develop methods for delivering powder aerosols of adenosine receptor agonists to sensitised guinea pigs (as a model of allergic asthma) and evaluate their effect as challenge agents for the measurement of airway responsiveness. "

12/09/1994 - "The data obtained with these new N6-substituted adenosine receptor agonists emphasize the interest of such compounds in the treatment of pain."
04/01/2011 - "By contrast, the efficacy of adenosine and adenosine receptor agonists in treating pain in humans is unclear. "
05/01/2010 - "Changes induced by formalin pain in central alpha1-adrenoceptor density are modulated by adenosine receptor agonists."

01/01/2010 - "Data on successful use of postconditioning in patients with acute myocardial infarction and cardiac surgery patients are also presented and possibility of clinical use of adenosine receptor agonists and opioids is discussed."
06/01/2013 - "Adenosine and dipyridamole are nonselective adenosine receptor agonists that have been associated with myocardial infarction (MI) during intravenous infusion. "
01/01/2003 - "Hence, A(2B) adenosine receptor agonists could be useful in the treatment of cardiac diseases like hypertension or myocardial infarction and in the management of septic shock, while antagonists may serve as novel drugs for asthma, Alzheimer's disease, cystic fibrosis and type-II diabetes. "

05/01/1994 - "Stimulation of chloride secretion by P1 purinoceptor agonists in cystic fibrosis phenotype airway epithelial cell line CFPEo-."
11/25/1993 - "ATP and A1 adenosine receptor agonists mobilize intracellular calcium and activate K+ and Cl- currents in normal and cystic fibrosis airway epithelial cells."
01/01/2003 - "Hence, A(2B) adenosine receptor agonists could be useful in the treatment of cardiac diseases like hypertension or myocardial infarction and in the management of septic shock, while antagonists may serve as novel drugs for asthma, Alzheimer's disease, cystic fibrosis and type-II diabetes. "