Granulomatous Mastitis

A rare, benign, inflammatory breast disease occurring in premenopausal women shortly after a recent pregnancy. The origin is unknown but it is commonly mistaken for malignancy and sometimes associated with BREAST FEEDING and the use of ORAL CONTRACEPTIVES.

Also Known As:

Networked: 95 relevant articles (5 outcomes, 6 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Carcinoma (Carcinomatosis)
2.	Mastitis
3.	Breast Diseases (Breast Disease)
4.	Breast Neoplasms (Breast Cancer)
5.	Tuberculosis (Tuberculoses)

Experts

1.	Altintoprak, Fatih: 5 articles (11/2015 - 09/2011)
2.	Kivilcim, Taner: 4 articles (11/2015 - 01/2013)
3.	Akcay, Mufide Nuran: 2 articles (10/2015 - 01/2015)
4.	Bouton, Marcia E: 2 articles (08/2015 - 01/2015)
5.	Jayaram, Lakshmi: 2 articles (08/2015 - 01/2015)
6.	Komenaka, Ian K: 2 articles (08/2015 - 01/2015)
7.	Celebi, Fehmi: 2 articles (11/2014 - 01/2013)
8.	Graveleau, J: 2 articles (06/2013 - 05/2013)
9.	Néel, A: 2 articles (06/2013 - 05/2013)
10.	Hamidou, M: 2 articles (06/2013 - 05/2013)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Granulomatous Mastitis:

1.	SteroidsIBA 09/01/2011 - "In this report, we present a patient with granulomatous mastitis who was treated successfully with low-dose oral and topical steroids. " 11/01/2015 - "Topical Steroids Are Effective in the Treatment of Idiopathic Granulomatous Mastitis." 10/01/2014 - "Can Steroids plus Surgery Become a First-Line Treatment of Idiopathic Granulomatous Mastitis?" 09/01/2011 - "Topical steroids to treat granulomatous mastitis: a case report." 06/01/2011 - "[Idiopathic granulomatous mastitis treated with steroids and methotrexate]."
2.	CosmeticsIBA 06/01/2006 - "As long as good cosmetic results can be achieved, surgical excision is quick, safe and effective treatment method for idiopathic granulomatous mastitis."
3.	Anti-Bacterial Agents (Antibiotics)IBA 11/01/2000 - "After not responding to antibiotics and incisional drainage, the biopsy-proved granulomatous mastitis improved with corticosteroid treatment. "
4.	Immunoglobulin M (IgM)IBA 07/01/2015 - "As a comparative study between conservative treatment protocols and surgical ones for patients with idiopathic granulomatous mastitis (IGM), this study is the largest to date. " 07/01/2015 - "The purpose of this study was to analyze the clinical features and demographic data of patients with idiopathic granulomatous mastitis (IGM) and to compare the results of conservative versus surgical treatment protocols. " 10/01/2014 - "The aim of this study is to compare the clinical course of idiopathic granulomatous mastitis (IGM) treated with low-dose oral corticosteroid therapy alone as opposed to treatment with low-dose corticosteroid therapy followed by surgery. " 08/01/2015 - "Idiopathic granulomatous mastitis (IGM) is becoming more commonly recognized and reported more often. " 04/01/2015 - "Idiopathic granulomatous mastitis (IGM) is a rare benign inflammatory disease of the breast. "
5.	tebufenozide (Mimic)IBA 01/01/2013 - " case is reported because it illustrates how idiopathic granulomatous mastitis can mimic other diseases, making it difficult to associate the presenting symptoms and the correct diagnosis; This disease is a challenge for clinicians to diagnose, manage and avoid iatrogenic complications, and requires consultation with experts in several specialties. " 03/01/2010 - "To study fine needle aspiration cytologic features of granulomatous mastitis (GM), which can clinically mimic a carcinoma of the breast. " 12/16/2014 - "Idiopathic granulomatous mastitis is a rare chronic inflammatory lesion of the breast that can clinically and radiographically mimic breast carcinoma. " 12/01/2014 - "Granulomatous mastitis presents a challenging clinical scenario, because it can mimic carcinoma. " 11/17/2007 - "Granulomatous mastitis is a rare disorder that may mimic breast carcinoma. "
6.	Methotrexate (Mexate)FDA LinkGeneric 11/01/2011 - "Methotrexate in the management of idiopathic granulomatous mastitis: review of 108 published cases and report of four cases." 11/01/2011 - "Is methotrexate an acceptable treatment in the management of idiopathic granulomatous mastitis?" 07/01/2009 - "First report of idiopathic granulomatous mastitis treated with methotrexate monotherapy." 04/01/2003 - "Methotrexate in the management of granulomatous mastitis." 06/01/2011 - "We report three cases of idiopathic granulomatous mastitis diagnosis and treatment based on prednisone until clinical improvement and methotrexate as maintenance therapy. "
7.	AntigensIBA 01/01/2013 - "This study aimed to investigate the autoimmune basis of idiopathic granulomatous mastitis (IGM) by determining the anti-nuclear antibody (ANA) and extractable nuclear antigen (ENA) levels of patients diagnosed with IGM. "
8.	Prednisone (Sone)FDA LinkGeneric 08/01/1994 - "In only one case was a specific diagnosis of granulomatous mastitis rendered based on the results of the biopsy; this patient received oral prednisone with prompt shrinkage of the breast mass to 20% of its original size. " 09/30/1993 - "[Granulomatous mastitis in a patient treated with prednisone]." 10/02/1980 - "Prednisone management of granulomatous mastitis." 06/01/2011 - "We report three cases of idiopathic granulomatous mastitis diagnosis and treatment based on prednisone until clinical improvement and methotrexate as maintenance therapy. "
9.	Bromocriptine (Parlodel)FDA LinkGeneric 01/01/2015 - "Temporal resolution of idiopathic granulomatous mastitis with resumption of bromocriptine therapy for prolactinoma." 04/01/2014 - "An SLE patient with prolactinoma and recurrent granulomatous mastitis successfully treated with hydroxychloroquine and bromocriptine." 08/01/2015 - "We report on a 28-year-old Chinese woman with a history of granulomatous mastitis 7 years previously and oligomenorrhoea, headache, blurred vision, and raised prolactin level 2 years previously, that was diagnosed as prolactinoma and treated conservatively with bromocriptine. "
10.	Adrenal Cortex Hormones (Corticosteroids)IBA 05/01/2015 - "Management of granulomatous mastitis: a series of 13 patients who were evaluated for treatment without corticosteroids." 09/01/2010 - "In this paper, we aimed to present two young women with granulomatous mastitis accompanied by erythema nodosum and successfully treated with corticosteroids. " 01/01/2007 - "We present a case of a young woman with idiopathic granulomatous mastitis, initially mistaken for mastitis as well as breast carcinoma, and successfully treated with a course of corticosteroids. "

Therapies and Procedures

1.	Mastectomy (Mammectomy) 07/01/2004 - "A greater awareness of the rare entity of idiopathic granulomatous mastitis is mandatory to avoid unnecessary mastectomies. " 07/01/2004 - "One patient underwent mastectomy upon clinical, mammographic, and repeated cytologic findings consistent with malignancy, and the final histology confirmed idiopathic granulomatous mastitis with no evidence of malignancy. " 07/01/2004 - "Idiopathic granulomatous mastitis: time to avoid unnecessary mastectomies." 12/01/2011 - "Idiopathic granulomatous mastitis: successful treatment by mastectomy and immediate breast reconstruction."
2.	Body Piercing (Piercing, Body) 06/01/2004 - "Gordonia terrae-induced suppurative granulomatous mastitis following nipple piercing."
3.	Mammaplasty (Breast Reconstruction) 12/01/2011 - "Idiopathic granulomatous mastitis: successful treatment by mastectomy and immediate breast reconstruction."
4.	Injections 07/06/1968 - " two of the cases repeated injections of silicone fluid were followed by extensive bilateral granulomatous mastitis. "