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Decorin

A small leucine-rich proteoglycan that interacts with FIBRILLAR COLLAGENS and modifies the EXTRACELLULAR MATRIX structure of CONNECTIVE TISSUE. Decorin has also been shown to play additional roles in the regulation of cellular responses to GROWTH FACTORS. The protein contains a single glycosaminoglycan chain and is similar in structure to BIGLYCAN.
Also Known As:
Bone Proteoglycan II; DSPG-II; Proteoglycan II, Bone
Networked: 947 relevant articles (40 outcomes, 163 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Iozzo, Renato V: 79 articles (02/2022 - 03/2002)
2. Schaefer, Liliana: 24 articles (01/2021 - 03/2002)
3. Neill, Thomas: 19 articles (02/2022 - 12/2010)
4. Owens, Rick T: 17 articles (04/2014 - 02/2005)
5. Logan, Ann: 11 articles (01/2021 - 09/2013)
6. Buraschi, Simone: 10 articles (01/2021 - 12/2010)
7. Seidler, Daniela G: 10 articles (05/2013 - 08/2004)
8. Timens, Wim: 8 articles (01/2021 - 03/2005)
9. Tredget, Edward E: 8 articles (01/2021 - 05/2011)
10. Baghy, Kornélia: 8 articles (01/2020 - 03/2011)

Related Diseases

1. Fibrosis (Cirrhosis)
2. Cicatrix (Scar)
3. Neoplasms (Cancer)
4. Breast Neoplasms (Breast Cancer)
5. Neoplasm Metastasis (Metastasis)

Related Drugs and Biologics

1. Collagen
2. Proteoglycans (Proteoglycan)
3. Biglycan
4. Transforming Growth Factor beta (TGF-beta)
5. Messenger RNA (mRNA)
6. Oligodeoxyribonucleotides
7. Liposomes (Liposome)
8. Proteins (Proteins, Gene)
9. Versicans (Versican)
10. Transforming Growth Factor beta1 (TGF beta 1)

Related Therapies and Procedures

1. Therapeutics
2. Laminectomy
3. Immunotherapy
4. Injections
5. Tissue Scaffolds