Inhalant Abuse

Illicit use of chemicals and products whose vapors can be inhaled to produce a rapid mind-altering effect. Inhalants include aerosols, gases, and volatile solvents that are often inhaled repeatedly to achieve the short-lived intoxicating effect.

Also Known As:

Networked: 75 relevant articles (2 outcomes, 10 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Polyneuropathies (Polyneuropathy)
2.	HIV Infections (HIV Infection)
3.	Kaposi Sarcoma (Kaposi's Sarcoma)
4.	Birth Weight (Birth Weights)
5.	Renal Tubular Acidosis (Distal Renal Tubular Acidosis)

Experts

1.	Bowen, Scott E: 7 articles (04/2010 - 01/2005)
2.	Hannigan, John H: 5 articles (04/2010 - 01/2005)
3.	Sarici, S Umit: 4 articles (01/2005 - 08/2002)
4.	Irtenkauf, Susan: 3 articles (04/2010 - 11/2007)
5.	Türkbay, Tümer: 3 articles (01/2003 - 08/2002)
6.	Batis, Jeffery C: 2 articles (11/2006 - 01/2005)
7.	Akay, Cemal: 2 articles (01/2003 - 08/2002)
8.	Gökçay, Erdal: 2 articles (01/2003 - 10/2002)
9.	Denli, Metin: 2 articles (01/2003 - 08/2002)
10.	Dündaröz, M Ruşen: 2 articles (10/2002 - 08/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Inhalant Abuse:

1.	TolueneIBA 04/01/2010 - "The data to date suggest that the high levels of toluene exposure typical with inhalant abuse are more detrimental to fetal development than typical occupational exposure, and preclinical paradigms can be beneficial for investigating the processes and risks of prenatal solvent exposure. " 11/01/2007 - "The present study assessed the tissue toluene levels attained following brief toluene exposures using a pre-clinical rat model of maternal inhalant abuse. " 01/01/1987 - "Exposure to concentrations of toluene similar to those used in this study occurs during organic solvent abuse and glue sniffing in humans." 06/15/2011 - "Based on this analysis, we sought to determine parameters by which glue-sniffing (toluene inhalation) behavior may be verified. " 04/01/2009 - "These results indicate that animals exposed prenatally to levels and patterns of toluene typical of inhalant abuse are at increased risk for skeletal and soft tissue abnormalities."
2.	n-hexaneIBA 11/01/1997 - "We describe a patient with a severe subacute neuropathy following n-hexane exposure via glue sniffing. " 11/01/1997 - "n-Hexane neuropathy has been described after glue sniffing and industrial exposure. " 03/01/1975 - "A young man with a long history of addictive glue-sniffing developed severe distal symmetrical polyneuropathy several months after switching to a cement containing n-hexane and gradually improved several months after switching to another cement containing no n-hexane. " 01/01/2012 - "Exposure to n-hexane, a neurotoxic solvent, has been associated with sensorimotor polyneuropathy, both in occupationally exposed workers and in glue-sniffing addicts. " 11/01/1986 - "Two cases of n-hexane polyneuropathy due to glue sniffing were reported and the clinical features, laboratory data and sural nerve biopsy findings were discussed. "
3.	SolventsIBA 04/01/2003 - "Data from intracranial self-stimulation studies of solvents may be useful in abuse potential assessment of individual compounds and for examining neural and behavioral processes involved in inhalant abuse." 04/01/2010 - "While substantial research has been done on the reproductive effects of occupational exposures to organic solvents, more research is needed on the outcomes and mechanisms of exposures typical of inhalant abuse." 07/01/2005 - "Glue sniffing refers to the deliberate inhalation of volatile solvents, commonly found in adhesives, for the purpose of intoxication. " 01/01/2005 - "Inhalant abuse is common and is facilitated by the widespread availability of volatile solvents that have legitimate commercial or household uses. " 01/01/2000 - "Organic solvents and glue sniffing and drug dependency increased again in 1999. "
4.	HydrocarbonsIBA 06/01/2014 - "Search terms included combinations of the following: hydrocarbons, inhalants, encephalopathy, coma, cognitive deficits, inhalant abuse, huffing, sudden sniffing death, toluene, renal tubular acidosis, metabolic acidosis, arrhythmia, dermatitis, and aspiration pneumonitis. " 08/01/1987 - "Widely disparate substances such as glue, gasoline, anesthetic gases, and nitrites have all been discussed under the single rubric of "inhalant abuse." A classification scheme is proposed which differentiates users of substances such as volatile hydrocarbons (gasoline, glue, etc.) from users of the anesthetic gases and of the amyl and butyl nitrites. " 07/01/1994 - "In the present study we attempted to investigate the influence of glue thinner, a very popular glue used by glue-sniffing children, and the four organic solvents that compose this thinner (toluene, mixture of petroleum hydrocarbons, ethyl acetate, methylene chloride) on self-stimulation of the lateral hypothalamus (ICSS) in rats. "
5.	Methanol (Carbinol)IBA 10/01/2006 - "We performed a prospective observational study of 7 subjects who presented to an ED after inhalant abuse of methanol-containing hydrocarbon products. " 03/01/2009 - "Methanol toxicity secondary to inhalant abuse in adult men." 10/01/2006 - "Inhalant abuse of methanol-containing products has increased over the last decade. "
6.	Trichloroethylene (Trichloroethene)IBA 01/01/2007 - "In a study the case of an acute intoxication following inhalant abuse of trichloroethylene vapours is presented. "
7.	Petroleum (Crude Oil)IBA 07/01/1994 - "In the present study we attempted to investigate the influence of glue thinner, a very popular glue used by glue-sniffing children, and the four organic solvents that compose this thinner (toluene, mixture of petroleum hydrocarbons, ethyl acetate, methylene chloride) on self-stimulation of the lateral hypothalamus (ICSS) in rats. "
8.	Methylene Chloride (Dichloromethane)IBA 07/01/1994 - "In the present study we attempted to investigate the influence of glue thinner, a very popular glue used by glue-sniffing children, and the four organic solvents that compose this thinner (toluene, mixture of petroleum hydrocarbons, ethyl acetate, methylene chloride) on self-stimulation of the lateral hypothalamus (ICSS) in rats. "
9.	Malondialdehyde (Propanedial)IBA 01/01/2003 - "In this study, we aimed to determine the levels of antioxidant enzymes and malondialdehyde in children with inhalant abuse. "
10.	EnzymesIBA 01/01/2003 - "Antioxidant enzymes and lipid peroxidation in adolescents with inhalant abuse." 01/01/2003 - "In this study, we aimed to determine the levels of antioxidant enzymes and malondialdehyde in children with inhalant abuse. "

Therapies and Procedures

1.	Anesthesia 01/01/2005 - "The literature regarding mothball abuse as well as inhalant abuse relevant to anesthesia is reviewed, and suggestions for the diagnosis and peri-operative management are offered."